A patient presents with bilateral exophthalmos, heat intolerance, weight loss, and an enlarged thyroid gland. Which condition is most likely?

 # A patient presents with bilateral exophthalmos, heat intolerance, weight loss, and an enlarged thyroid gland. Which condition is most likely?

A. Myxedema

B. Grave’s disease

C. Cushing’s syndrome

D. Addison’s disease

The most likely condition is B. Graves’ disease.

Explanation:

• Bilateral exophthalmos (bulging eyes), heat intolerance, weight loss, and enlarged thyroid gland (goiter) are hallmark symptoms of Graves’ disease, an autoimmune disorder causing hyperthyroidism. It results from thyroid-stimulating antibodies that overactivate the thyroid, leading to excess thyroid hormone production.
• Myxedema (A) is associated with hypothyroidism, presenting with symptoms like weight gain, cold intolerance, and fatigue, not matching the patient’s symptoms.
• Cushing’s syndrome (C) involves excess cortisol, leading to weight gain (often central), moon face, and hypertension, but not typically exophthalmos or thyroid enlargement.
• Addison’s disease (D) is adrenal insufficiency, causing weight loss, fatigue, and hypotension, but it lacks exophthalmos or thyroid involvement.

Thus, Graves’ disease best fits the clinical presentation.